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When a doctor tries to bend the person's forearm back or straighten it out, the arm resists being moved and, when it moves, moves it starts and stops, as it is being ratcheted (called cogwheel rigidity).

Neither works well together with MAO inhibitors such as isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline or tranylcypromine.

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