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I've been on Gleevec since September 2007 for Chronic Myelogenous Leukemia. And I can say that I didn't have any problems with iron level, but maybe I am an exception. However I know many more people who had no problems with their iron while being on Gleevec. Before it I was on another medication but it was not effective at all and had serious side effects for me. but my doctor persuaded me that it was the best possible medication in my case and it had helped many people get on lasting remission. However, it caused me to vomit from time to time, besides I had severe leg cramping and that would make me crazy. In the night I needed several blankets to calm down the cramping and fall asleep. Sometimes I spent sleepless nights and felt incredibly weak and passive next day, especially if I vomited before and had absolutely no energy to live the day out. So after 2 months I insisted on switching to another medication and he put me on Gleevec. I consider it to be a lucky decision and I am happy that this medication is so effective for me and causes no additional problems.
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I had a 5 cm Gastrointestinal Stroma Tumor removed from my stomach about a year ago and have been on Gleevec 400 mg since Nov. 2012. Main side effects are occasional muscle cramping that can be intense, mild periorbital edema, mild-moderate nausea. Most worrisome for me is a very low ANC (absolute neutrophil count) that is being closely monitored.

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