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My sister had auditory hallucinations all her life. Our family doctor is constantly raising the dosage and putting her on new medication because the previous stop being effective. But since we started on Invega, she is on the lowest dose and has hallucinations only once or twice a month. What is still more wonderful she has no side effects and can function almost like a healthy person. Great drug!

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After the stabilization phase, patients were randomized in a double-blind manner to either continue on Paliperidone Extended-Release Tablets at their achieved stable dose, or to placebo, until they experienced a relapse of schizophrenia symptoms.

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These types of data may also lead to the future revision of psychiatric diagnostic manuals based on a new understanding of the etiology of these disorders.

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AstraZeneca Pharmaceuticals, Bristol-Myers Squibb, Forest Pharmaceuticals, Janssen Pharmaceutica, Eli Lilly, Otsuka Pharmaceutical, Pfizer, Zenith Goldline Pharmaceuticals, Schering-Plough, and Novartis provided medications for the studies.

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Abbreviations: CGI-S, Clinical Global Impression-Severity; ITT, intent-to-treat; LOCF, last observation carried forward; ND, not determined; PANSS, Positive and Negative Syndrome Scale; PSP, personal and social performance; SD, standard deviation.

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